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所在位置:所有产品 > 抗体抗原 > 一抗 > NFATC2抗体
NFATC2抗体图片
产品货号:
Z22049
中文名称:
NFATC2抗体
英文名称:
Anti-NFATC2 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-NFATC2 Antibody
指标别名NF ATc2;NF ATp;NFAT pre existing subunit;NFAT1;NFATC2;NFATP
克隆性Polyclonal
检验物种human,mouse,rat
应用范围WB,ELISA
基因名称NFATC2
抗体来源Rabbit
抗体类型IgG
免疫原E.coli-derived human NFAT1 recombinant protein (Position:Q594-H676).
实际分子量100KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料NFATC2(Nuclear factor of activated T-cells,cytoplasmic 2),also known as NFATP or the 'preexisting component' of NFAT,is present in the cytosolic fraction of unstimulated T cells,which is also a member of the nuclear factor of activated T cells (NFAT) family.The NFATC2 gene is mapped on 20q13.2.NFATC2 is highly homologous to NFATC1 over a limited domain which shows similarity to the Dorsal/Rel family but has a wider tissue distribution.Ectopic expression of NFATC2 inhibited the basal activity of the human CDK4 promoter.Additionally,both Calna-/- and Nfatc2 -/- mice had elevated protein levels of Cdk4,confirming a negative regulatory role for the calcineurin/NFAT pathway.NFATC2 controls myoblast fusion at a specific stage of myogenesis after the initial formation of a myotube and is necessary for further cell growth.Overexpression of NFATC2 promoted differentiation of osteoclast precursor cells into tartrate-resistant acid phosphatase-positive (TRAP-positive) multinucleated osteoclast-like cells even in the absence of RANKL.
Uniprot IDQ13469
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
推荐稀释比
Western blot(WB) 1:500~2000
(ELISA): 1:100~1000

相关搜索:NFATC2抗体NFATC2多抗Anti-NFATC2 Antibody
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