产品货号：
Z22049
中文名称：
NFATC2抗体
英文名称：
Anti-NFATC2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NFATC2 Antibody |
| 指标别名 | NF ATc2;NF ATp;NFAT pre existing subunit;NFAT1;NFATC2;NFATP |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ELISA |
| 基因名称 | NFATC2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human NFAT1 recombinant protein (Position:Q594-H676). |
| 实际分子量 | 100KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | NFATC2(Nuclear factor of activated T-cells,cytoplasmic 2),also known as NFATP or the 'preexisting component' of NFAT,is present in the cytosolic fraction of unstimulated T cells,which is also a member of the nuclear factor of activated T cells (NFAT) family.The NFATC2 gene is mapped on 20q13.2.NFATC2 is highly homologous to NFATC1 over a limited domain which shows similarity to the Dorsal/Rel family but has a wider tissue distribution.Ectopic expression of NFATC2 inhibited the basal activity of the human CDK4 promoter.Additionally,both Calna-/- and Nfatc2 -/- mice had elevated protein levels of Cdk4,confirming a negative regulatory role for the calcineurin/NFAT pathway.NFATC2 controls myoblast fusion at a specific stage of myogenesis after the initial formation of a myotube and is necessary for further cell growth.Overexpression of NFATC2 promoted differentiation of osteoclast precursor cells into tartrate-resistant acid phosphatase-positive (TRAP-positive) multinucleated osteoclast-like cells even in the absence of RANKL. |
| Uniprot ID | Q13469 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 (ELISA)： 1:100～1000 |
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